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KMID : 0378019760190040565
New Medical Journal
1976 Volume.19 No. 4 p.565 ~ p.571
Disappearance of an Arrhythmia by Intravenous Lidocaine


Abstract
Anesthesiologists are often encountered an arrhythmia during general anesthesia. Sometimes, ventricular arrhythmia may threaten the patient condition to be fatal.
On the contrary, anesthesiologists experience that an arrhythmia which existed pre-operatively may disappear during and/or after general anesthesia. The mechanism of disappearance of an arrhythmia during general anesthesia is not known clearly at this moment. In most of the cases, the pre-operative arrhythmia may reappear after general anesthesia.
Incidence of an arrhythmia during general anesthesia was varied among the reported references. But no one reported disappearance of an arrhythmia during and/or after general anesthesia. In the previous authors report, the incidence of an arrhythmia was 25.8% and disappearance of an arrhythmia (existed pre-operative arrhythmia) was 64. 3% during general anesthesia, respectively. In this fact, disappearance of an arrhythmia may last forever or not is an interesting focus to anesthesiologists.
Ventricular arrhythmia patient was underwent general anesthesia for cholecystectomy.
In this patient, ventricular premature contraction was not disappeared by 100 mg of lidocaine intravenous injection preoperatively. Inhalation anesthesia with halothane-N2O-O2 was performed under endotracheal anesthesia. An arrhythmia was not abolished during general anesthesia.
1% lidocaine intravenous infusion was carried out through the recovery period. An arrhythmia was disappeared after 300mg of lidocaine intravenous infusion during 5 hours period. Antiarrhythmic effect of lidocaine was observed.
An arrhythmia which ventricular premature contraction was disappeared after general anesthesia with 400 mg of lidocaine (total dose) intravenously.
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